Retinol Complex 0.25SkinMedica's Age Defense Retinol Complex . 25 is formulated to renew the skin's tone and texture without irritating the skin. Retinol helps combat the signs of premature aging while magnolia bark extract soothes inflammation. Ideal for use twice a week to build tolerance to formula. Key Ingredients: Retinol: helps boost collagen production and cell turnover to reduce the appearance of fine lines and deep wrinkles PhytoShield Complex: an antioxidant