GA131015: Fmoc-Thr(Neu5Acα(2-6)GalNAc)-OH (Peracetate, Benzyl Ester)Tumor Associated Carbohydrate Antigen (TACA). STn is a sialylated form of the truncated O glycosylated core determinant Tn with structure: Neu5Ac2 6GalNAc O Ser Thr. STn results from an early sialylation of the Tn antigen due to overexpression of the enzyme STn synthase (ST6GalNAc I) and or disruption of further glycan elongation processes. STn is negligibly expressed in healthy tissues but overexpressed in >80% of human carcinomas. As such, STn is
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